Age-Defying Night Cream (NeriumAD® Formula)

Reveal radiant and youthful-looking skin with Nerium’s clinically tested Age-Defying Night Cream – a flagship age-fighting product, containing the highest concentration of our exclusive, patented NAE-8® extract.

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  • Details
  • How To Use
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  • Real Results


Resist the signs of aging skin with our clinically tested, age-fighting Night Cream containing a high concentration of our exclusive, patented NAE-8® extract.

Age-Defying Night Cream, featuring our exclusive, patented NAE-8® extract:

  • Addresses both the signs of aging as well as the causes
  • Acts as a powerful antioxidant and works to target free radical damage
  • Boosts the cell renewal process to reveal younger-looking skin
  • Targets the causes of skin-damaging inflammation
  • Perfect for use on face, neck, décolletage and hands
  • Ideal for all skin types (non-comedogenic and dermatologist-tested)

How To Use

Age-Defying Night Cream (NeriumAD® Formula)

After thoroughly cleansing skin, apply 4-5 pumps of product to face and neck. Apply to slightly damp skin for optimal absorption. Rinse the skin morning following usage.



A patented proprietary extract and powerful antioxidant derived from nerium oleander and aloe vera that helps reduce the appearance of fine lines and wrinkles.

Peptide Matrix

A blend of collagen, elastin and glycosaminoglycan that helps restore skin’s firmness.

Vitamin E

A potent antioxidant that helps protect the skin from free radicals and UV damage.

Rice Bran Oil

Rich in vitamin E and fatty acids; helps fight free radicals.

Castor Seed Oil

A natural, super-hydrating oil that softens the skin.

Hydrolyzed Quinoa

Helps guard against environmental stressors and soothes irritated skin.

Aloe Barbadensis Leaf Juice

A juice extracted from the aloe vera plant that contains many beneficial components including polysaccharides, which are responsible for skin’s natural ability to hydrate and retain water; glycoproteins, which play an important role in supporting the core structure of the skin matrix; and vitamins A (beta-carotene), C and E, which are potent antioxidants.

Full ingredient list:

NAE-8 Nerium Aloe Extract (Aloe Barbadensis Leaf Juice, Nerium Oleander Leaf), Peptide Matrix (Collagen, Elastin, Glycosaminoglycans), Oryza Sativa (Rice) Bran Oil, Stearic Acid, Glycerin, C14-22 Alcohols, Glyceryl Stearate, Ricinus Communis (Castor) Seed Oil, Cetyl Alcohol, Olus Oil, Cetearyl Glucoside, Cetearyl Alcohol, Sodium Borate, Carrageenan, Dicaprylyl Ether, Hydrolyzed Quinoa, Sodium Isostearoyl Lactylate, Dimethicone, Carrageenan, C12-20 Alkyl Glucoside, Water (Aqua), Sodium PCA, Caprylyl Glycol, Fragrance (Parfum), Glyceryl Caprylate, Tocopherol, Phenylpropanol, Sodium Hydroxymethylglycinate.

Real Results

In independently conducted clinical trials:


of participants showed significant improvement in the appearance of their wrinkles.


showed improvement in their skin’s radiance.


of participants showed significant improvement in skin discoloration.